Sunday, September 23, 2012
No Fat Mice in This Lab
Two microRNAs have been identified as potential therapeutic targets for obesity. Researchers at Virginia Tech and the University of Texas Southwestern Medical Center at Dallas have shown that mice genetically engineered to lack microRNA-378 (miR-378) and miR-378* are remarkably resistant to obesity when fed a high-fat diet, and are metabolically more capable of converting food into energy than wild-type littermates....
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