Targeted probiotics could affect the physiology of human fat cells and potentially prevent or help treat conditions such as obesity, according to new Irish research.
Recently published in Microbiology, the study from scientists at Teagasc (the Irish Agriculture and Food Development Authority), University College Cork and the Alimentary Pharmabiotic Centre examined whether a lactobacillus strain with CLA (conjugated linoleic acid) influenced fat tissue composition in mice.
Previous research from Racine et al. (2010) and Thom et al. (2001) has linked fatty acid t10, c12 CLA consumption with decreased body fat in humans, while other studies suggest that this type of fatty acid inhibits colon cancer cell growth.
Probiotics assists CLA metabolism
In this study, scientists transferred an enzyme-encoding gene from skin bacterium P.acnes to Lactobacillus paracasei and induced it to produce CLA t10, c12, which fed to mice resulted in a fourfold increase of CLA in mouse fat tissue composition (against a second probiotic control strain) showing that live bacteria intake affects metabolism at remote body sites...
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