Poor biological clock leads to obesity

UC San Diego biologists have discovered biological clocks of mammals are related to development of obesity and diabetes.

It also raises the possibility that some of the rise in diabetes could be a consequence of disturbances in sleep-wake cycles from our increasingly around-the-clock lifestyles.

"We know that mice that don't have good biological clocks tend to develop diabetes and obesity. And we know that mice that have developed diabetes and obesity tend not to have very good biological clocks," Nature quoted Steve Kay at UC San Diego, as saying.

"But what we found that's so significant is that a particular biological clock protein, cryptochrome, is actually regulating how the hormone that regulates glucose production in the liver works in a very specific way," he added.

The study also indicates why shift workers, whose biological clocks are often out of step, also have a greater risk of developing obesity and insulin resistance...