Scientists have used experimental drugs being developed by Pfizer to reset and restart the body clock of mice in a lab and say their work may offer clues on a range of human disorders, from jetlag to bipolar disorder.
The drugs, which are not yet available in a form suitable for humans and could take many years to develop into human medicines, work by altering the activity of an enzyme which helps set the speed of the body clock.
Researchers say they could potentially restore rhythms in people whose body clocks are messed up by shift work, or in psychiatric disorders like depression, and may even have implications for metabolic problems such as obesity...
Sunday, September 05, 2010
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